Spend some time with the search function here...it's been talked about a lot.
Here is the jist of prepping an engine for boost the RIGHT way.
First off, you want LOW compression. Otherwise you will have to run premium or higher fuel, and maybe even water injection to keep it from detonating. 10.5:1 is pretty high for boost. You are better off with 9:1 or even 8.5:1
Secondly, you REALLY want to use forged pistons at least. The amount of heat that gets generated in forced induction, even a good Hypereutectic piston is going to be "OK" under very low boost conditions for a while. But in most cases is still a time bomb. I don't know that you would need to have forged rods and forged crank, being you don't sound like you want to run extreme power. But a good set of quality rods at least. Not knowing what your "big" cam is, it could be fine, or it could be garbage for a forced induction application. But the simple science of cams is backwards for forced induction vs naturally aspirated engines. So a huge cam with a lot of lift and duration isn't as efficient.
But .40 over.... **From what I have read about this block**, the cylinder walls are pretty thin on this engine to start with. So going .40 over is pretty drastic for boost. Does this mean you will blow out your piston wall? Maybe not. But it does mean that you will run hotter, as there isn't as much material left to dissipate the heat as quickly. This increases the odds of detonation as well. Also, you want your cylinders machined with the right tolerances for forced induction to compensate for the heat. Which means that it's bored SLIGHTLY larger.
So a great idea? Maybe not. Impossible? Definitely not.
Rebuild engine with dished pistons.
Have rotating assembly bore aligned. (eliminates vibration which kills main bearings.)
Talk to your machine shop about the specs of your cam to determine if it will be beast or burden.
Lastly don't expect to run big boost. 4-6lbs could be safe to start.
You are going to need at least:
fuel pressure regulator
upgraded spark
engine management? - Will the awesome stock ECU have the flexibility for added fuel/air and timing requirements?
It's a start.... Good luck.